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Pharmacological Biotechnology

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Biotecnologie Farmacologiche

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Academic year 2021/2022

Course ID
BIO0170A Pds 306-TB
Teachers
Prof.ssa Carola Eva
Dott.ssa Alessandra Oberto
Degree course
[0101M21] Molecular Biotechnology
Year
2nd year
Teaching period
First semester
Type
Related or integrative
Credits/Recognition
3
Course disciplinary sector (SSD)
BIO/14 - farmacologia
Delivery
Blended
Language
English
Attendance
Obligatory
Type of examination
Oral
Type of learning unit
modulo
Modular course
PHARMACOLOGY AND DRUG THERAPIES (BIO0170 Pds 306-TB)
Prerequisites
Basic concepts of biology and chemistry. Basic principles for the actions of drugs.
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Sommario del corso

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Course objectives

Starting from the fundamentals acquired in the Bachelor degree, this master course addresses the therapeutic activity of drugs employed in neurological disease and drug used to treat  inflammation.

The course provides also insights on:

-history, development, pharmacodynamics and pharmacokinetics of biotechnology drugs

-brain-gut axis as a possible field of interst for drug development

-animal behavior in mice to analyze of drug activity on the central nervous system

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Results of learning outcomes

At the end of the course the students will be able to understand how drugs affect the organism and to investigate how biological systems fail to function, providing information on the etiology of some disease and of some disease symptoms.

The students will learn the drug molecular activity on major neurological desease and know how to perform and perceive the intended meaning of behavioral study in animal models for testing drug activity on the nervous sistem. They will be able to recognize and understand the therapeutic use of new biotechnological drugs.

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Program

Drugs acting on the CNS

Drugs acting on the immune system

Biotechnological drugs acting on CNS

Biotechnological drugs acting on immune system

Monoclonal antibodies

Genic therapy

Epigenetic drugs

Biotechnological drugs acting on bone metabolism

-Biotechnological drugs: Diabetes therapy, Follicle stimulating hormone (FSH), Interferons

- The brain-gut axis

- Behavioral pharmacology in laboratory rodents 

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Course delivery

The course is taught in English through frontal lesson. Given the current pandemic situation, the remote mode (Webex) is ensured throughout the academic year. Students for this purpose will receive a webex meeting invitation via email.

 

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Learning assessment methods

The exam will be in written form with an open question for each parts. Students have 30 minutes to complete the test.

The final mark is given by the weighted average with respect to the credits of each parts.

The learning verification methods may vary according to the limitations imposed by the current health crisis. In any case, the remote mode is guaranteed for the entire academic year.

Suggested readings and bibliography

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In addition to the material that will be distributed by the teacher, the following textbooks are suggested:

  • Vegeto E, Maggi A, Minghetti P, FARMACI BIOTECNOLOGICI-ASPETTI FARMACOLOGICI E CLINICI, CEA, Zanichelli 2020.
  • Francesco Clementi, Guido Fumagalli. General and Molecular Pharmacology. John Wiley & Sons Inc, 2015
  • Goodman & Gilman's manual of pharmacology and therapeut, ed: McGraw-Hill Education, 2013


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Notes

The procedures for carrying out teaching may vary according to the limitations imposed by the healthcare crisis. In any case it is assured the remote mode for the whole academic year.

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