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Pharmacological Biotechnology

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Pharmacological Biotechnology

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Academic year 2022/2023

Course ID
BIO0170A Pds 306-TB
Teaching staff
Prof.ssa Carola Eva
Dott.ssa Ilaria Bertocchi
Modular course
Degree course
[0101M21] Molecular Biotechnology
Year
2nd year
Teaching period
First semester
Type
Related or integrative
Credits/Recognition
3
Course disciplinary sector (SSD)
BIO/14 - pharmacology
Delivery
Blended
Language
English
Attendance
Obligatory
Type of examination
Written and oral
Prerequisites
Basic concepts of biology and chemistry. Basic principles of physiology and pharmacology (general pharmacology and drugs targets).
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Sommario del corso

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Course objectives

Starting from the fundamentals acquired in the Bachelor degree, this master course addresses the therapeutic activity of drugs employed in neurological disease and drug used to treat inflammation.

The course provides also insights on:

-history, development, pharmacodynamics and pharmacokinetics of biotechnology drugs

-brain-gut axis as a possible field of interest for drug development

-behavioral analysis in rodents to test drug activity on the central nervous system

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Results of learning outcomes

At the end of the course the students will be able to understand how drugs affect the organism and to investigate how biological systems fail to function, providing information on the etiology of some disease and of some disease symptoms.

The students will learn the drug molecular activity on major neurological desease and know how to perform and perceive the intended meaning of behavioral study in animal models for testing drug activity on the nervous sistem. They will be able to recognize and understand the therapeutic use of new biotechnological drugs.

In particular, the learning outcomes will be:

Knowledge and understanding ability
the Student will be able to learn and understand the topics of the pharmacology program

Applying knowledge and understanding
the Student will be able to apply the knowledge and to understand pharmacology with basic and applied research purposes

Independent Judgement
the Student will be able to develop a good judgment and analysis autonomy on pharmacological problems

Communication skills
the Student will be able to develop good communication skills and suitable language properties in the didactic field

Learning skills
the Student will be able to develop functional organizational and learning skills in future institutional settings (PhD)

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Course delivery

The course is taught in English through frontal lesson. Attendance is obligatory

 

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Learning assessment methods

The exam will be in the form of a presentation prepared and presented by the student

The final mark is given by the weighted average with respect to the credits of each parts.

 

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Program

Drugs acting on the CNS

Drugs acting on the immune system

Biotechnological drugs acting on CNS

Biotechnological drugs acting on immune system

Monoclonal antibodies

Genic therapy

Epigenetic drugs

Biotechnological drugs acting on bone metabolism

-Biotechnological drugs: Diabetes therapy, Follicle stimulating hormone (FSH), Interferons

- The brain-gut axis

- Behavioral pharmacology in laboratory rodents 

Suggested readings and bibliography

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In addition to the material that will be distributed by the teacher, the following textbooks are suggested:

  • Vegeto E, Maggi A, Minghetti P, FARMACI BIOTECNOLOGICI-ASPETTI FARMACOLOGICI E CLINICI, CEA, Zanichelli 2020.
  • Francesco Clementi, Guido Fumagalli. General and Molecular Pharmacology. John Wiley & Sons Inc, 2015
  • Goodman & Gilman's manual of pharmacology and therapeut, ed: McGraw-Hill Education, 2013


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Note

The procedures for carrying out teaching may vary according to the limitations imposed by the healthcare crisis. In any case it is assured the remote mode for the whole academic year.

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Last update: 29/09/2022 17:40
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