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PET/SPECT/CT
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PET/SPECT/CT
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Academic year 2023/2024
- Course ID
- BIO0242A Pds 308-BIDD
- Degree course
- [0101M21] Molecular Biotechnology
- Year
- 1st year
- Teaching period
- To be defined
- Type
- Distinctive
- Credits/Recognition
- 5
- Course disciplinary sector (SSD)
- MED/36 - diagnostic imaging and radiotherapy
- Delivery
- Formal authority
- Language
- English
- Attendance
- Obligatory
- Type of examination
- Oral
- Type of learning unit
- modulo
- Modular course
- BIOMEDICAL IMAGING (BIO0242 Pds 308-BIDD)
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Sommario del corso
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Course objectives
• To provide basic and advanced knowledge concepts in Nuclear Medicine and Molecular Imaging, applied both to basic science and clinical practice.
• To introduce the current and potential application of the different radiopharmaceuticals, applied both for diagnostic and therapeutic purposes. Namely, will be introduced the pre-clinical and clinical appliation of radio-ligand therapy in different cancer phenotypes.
• To introduce the concept of translational imaging ("from bench to the bedside").
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Results of learning outcomes
• Knowledge and applicability of different radiopharmaceuticals related to clinical oncology, neurology, basic science and cardiology.
• Completing the course, students should have learned the princiapl indications regarding different hybrid diagnostic techniques (PET/CT, PET/MRI, SPECT/CT) and be able to understand the potential clinical application and the usefulness in pre-clinical practice.
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Program
- Basic concepts of clinical application of PET and SPECT imaging in medicine.
- Overview about technical aspects of PET and SPECT tomographs.
- Overview about a pre-clinical (laboratory) and clinical (hospital) facilities for nuclear medicine and molecular imaging.
- Synthesis and Production of PET radiopharmaceuticals using a Gallium-68 Generator
- Synthesis and Production of PET radiopharmaceuticals using a cyclotron facility
- PET radiopharmaceuticals for imaging glucose metablosim
- PET radiopharmaceuticals for imaging different cancer phenotypes
- Clinical and Pre-clinical application of PET imaging in Endocrinology
- Clinical and Pre-clinical application of PET imaging in Neurology and degenerative disorders
- Clinical and Pre-clinical application of SPECT in Cardiology
- Clinical and Pre-clinical application of PET and SPECT imaging for investigating Neuroendocrine Tumors
- Theranostics approach in Neuroendocring Tumors trough the identification of the somatostatin receptors.
- Novel radiopharmaceuticals for PET imaging in prostate cancer (PSMA, choline, fluciclovine).
- Diagnostic application of inhibitor of the Fibroblast Activating Protein (FAPi) in PET imaging.
- Role of PET imaging in Hypoxia
- Clinical and preclinical application of PET imaging for evaluating the response to therapy in oncology, with a dedicated focus on Immunotherapy
- Theranostics approach for investigating the Gastrin Release Peptide Receptor (GRPR or Bombesin)
- Design and concept of Novel Radiopharmaceuticals: how does it work?
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Course delivery
40 hours, formal lectures.
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Learning assessment methods
Oral Test
Suggested readings and bibliography
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Students will receive lecturer presentations together with support material, including scientific review or original articles and/or book chapters specific for each lecture.
- Enroll
- Open
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