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PRINCIPLES OF DRUG DISCOVERY
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Principles of Drug Discovery
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Academic year 2022/2023
- Course ID
- BIO0214 Pds 308-BIDD
- Teacher
- Prof. Giuseppe Ermondi (Lecturer)
- Degree course
- [0101M22] Molecular Biotechnology
- Year
- 1st year
- Teaching period
- First semester
- Type
- Related or integrative
- Credits/Recognition
- 5
- Course disciplinary sector (SSD)
- CHIM/08 - pharmaceutical chemistry
- Delivery
- Formal authority
- Language
- English
- Attendance
- Obligatory
- Type of examination
- Written
- Prerequisites
- Background in peptides/protein structure, and basic knowledge of organic chemistry
- Propedeutic for
- Advanced Drug Discovery
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Sommario del corso
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Course objectives
Understanding the drug discovery process and its phases. Discuss in terms of structure-activity/property relationships (QSAR/QSPR) the pharmacodynamic and ADME-Tox behavior of some classes of drugs.
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Results of learning outcomes
Acquisition of the concept of drug and its characterization parameters. Acquisition of the concept of the multidisciplinarity and interdisciplinarity of the drug discovery process through the study of selected drug classes. Knowledge of some of the main experimental and computational methodologies used in medicinal chemistry.
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Course delivery
The registration to Moodel is free and mandatory to access to the course material.
A student is required to attain at least 75% of the attendance for lectures, tutorials and practical sessions of the course.
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Learning assessment methods
written examination with open-ended questions
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Support activities
in-depth multimedia material will be available to students
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Program
Drug target interaction.
Pharmacokinetics and ADME-Tox.
The drug discovery pipeline.
Drug development.
Methods for the determination of physicochemical and in-vitro ADME-Tox descriptors in drug discover.
Examples.
Suggested readings and bibliography
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Consultation
Basic Principles of Drug Discovery and Development
Autore: Benjamin BlassEdizione: 1st
Casa editrice: Academic Press
ISBN: 9780124115088
Url: https://www.elsevier.com/books/basic-principles-of-drug-discovery-and-development/blass/978-0-12-411508-8Papers suggested during the lessons
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