Dario Livio Longo
Contract Professor
- Department of Molecular Biotechnology and Health Sciences
- SSD: CHIM/03 - general and inorganic chemistry
- ORCID: orcid.org/0000-0002-6906-9925
Contacts
- +390116707431
- dario.longo@unito.it
dariolivio.longo@cnr.it - Institute of Biostructures and Bioimaging (IBB)
Italian National Research Council (CNR)
c/o MBC
Via Nizza, 52 Torino - https://www.molecularbiotechnology.unito.it/do/docenti.pl/Show?_id=dlongo
- Contacts VCard
At
- Department of Molecular Biotechnology and Health Sciences
- Dipartimento di Biotecnologie Molecolari e Scienze per la Salute
- Master Program in Molecular Biotechnology
Research products
All my research productsSelected research products
Anemone A, Consolino L, Arena F, Capozza M, Longo DL. (2019) Imaging tumor acidosis: a survey of the available techniques for mapping in vivo tumor pH. Cancer metastasis reviews 38(1-2) 25-49 [DOI PMID]
Consolino L, Longo DL, Sciortino M, Dastru W, Cabodi S, Giovenzana GB, Aime S. (2017) Assessing tumor vascularization as a potential biomarker of imatinib resistance in gastrointestinal stromal tumors by dynamic contrast-enhanced magnetic resonance imaging. Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20(4) 629-639 [DOI PMID]
Longo DL, Bartoli A, Consolino L, Bardini P, Arena F, Schwaiger M, Aime S. (2016) In Vivo Imaging of Tumor Metabolism and Acidosis by Combining PET and MRI-CEST pH Imaging. Cancer research 76(22) 6463-6470 [DOI PMID]
Consolino L, Longo DL, Dastru W, Cutrin JC, Dettori D, Lanzardo S, Oliviero S, Cavallo F, Aime S. (2016) Functional imaging of the angiogenic switch in a transgenic mouse model of human breast cancer by dynamic contrast enhanced magnetic resonance imaging. International journal of cancer 139(2) 404-13 [DOI PMID]
Longo DL, Arena F, Consolino L, Minazzi P, Geninatti-Crich S, Giovenzana GB, Aime S. (2016) Gd-AAZTA-MADEC, an improved blood pool agent for DCE-MRI studies on mice on 1 T scanners. Biomaterials 75 47-57 [DOI PMID]
Longo DL, Dastru W, Consolino L, Espak M, Arigoni M, Cavallo F, Aime S. (2015) Cluster analysis of quantitative parametric maps from DCE-MRI: application in evaluating heterogeneity of tumor response to antiangiogenic treatment. Magnetic resonance imaging 33(6) 725-36 [DOI PMID]
Longo DL, Di Gregorio E, Abategiovanni R, Ceccon A, Assfalg M, Molinari H, Aime S. (2014) Chemical exchange saturation transfer (CEST): an efficient tool for detecting molecular information on proteins' behaviour. The Analyst 139(11) 2687-90 [DOI PMID]
Longo DL, Busato A, Lanzardo S, Antico F, Aime S. (2013) Imaging the pH evolution of an acute kidney injury model by means of iopamidol, a MRI-CEST pH-responsive contrast agent. Magnetic resonance in medicine 70(3) 859-64 [DOI PMID]
Research topics
Dario Longo lab aims to develop novel magnetic resonance imaging (MRI)-based methods for characterizing tumor microenvironment properties (acidosis, vascularization, hypoxia) in murine tumor models. We are interested in developing and validating non-invasive MRI procedures and probes for improving diagnosis and assessment of treatment effects with a special focus on tumor metabolism and on antiangiogenic drugs.
Our current projects include:
- Imaging tumor acidosis and angiogenesis
- assessing pH imaging as a novel biomarker in cancer and in renal diseases
- development of novel MRI-based probes for assessing tumor microenvironment
More information about research activities can be found at:
Gruppi di ricerca
Imaging Tumor Microenvironment
Research groups
Thesis, work placement and internship offers