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Therapeutic biotechnology applied to regenerative medicine
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Therapeutic biotechnology applied to regenerative medicine
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Academic year 2022/2023
- Course ID
- BIO0216B Pds 306-TB
- Teacher
- Prof.ssa Benedetta Bussolati (Lecturer)
- Modular course
- THERAPEUTIC BIOTECHNOLOGY (BIO0216 Pds 306-TB)
- Degree course
- [0101M21] Molecular Biotechnology
- Year
- 2nd year
- Teaching period
- To be defined
- Type
- Distinctive
- Credits/Recognition
- 5
- Course disciplinary sector (SSD)
- MED/46 - medical and biotechnology laboratory techniques
- Delivery
- Formal authority
- Language
- English
- Attendance
- Obligatory
- Type of examination
- Oral
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Sommario del corso
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Course objectives
Knowledge of the molecular and cellular mechanisms involved in the pathogenesis of the main kidney diseases and of bio-technological techniques for their therapy.
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Results of learning outcomes
Knowledge of the molecular and cellular mechanisms involved in the pathogenesis of the main kidney diseases and of bio-technological techniques for their therapy, with specific focus on regenerative medicine.
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Course delivery
On-line Moodle support for knowledge on renal pathology and transplant.
Frontal lessons and presentation/discussion of literature papers for the molecular and biotechnological approaches for kidney regeneration.
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Learning assessment methods
Oral examination and discussion of the literature data.
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Program
- Pathogenetic mechanisms and development of molecular therapies:
Alterations of the immune system responsible for glomerular and tubulo-interstitial damage, autoimmunity, mechanism of the immune complex deposition. Strategies for the induction of tolerance. Mechanisms of glomerular permeability.
- Allotransplant:
molecular and cellular mechanisms involved in the main clinical complications, theory and methodology for the development of techniques aimed to induce a specific immuno-suppression, tolerance or to modify the organ immunogenicity.
-Regenerative medicine:
Resident and bone-marrow derived stem cells in the regeneration of the glomerular and tubular damage; stem cells and gene therapy, bioreactors.
Suggested readings and bibliography
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Didactic material (slides, text and articles) provided.
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Note
Le modalità di svolgimento dell'attività didattica potranno subire variazioni in base alle limitazioni imposte dalla crisi sanitaria in corso. In ogni caso è assicurata la modalità a distanza per tutto l'anno accademico
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