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Therapeutic biotechnology applied to regenerative medicine

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Therapeutic biotechnology applied to regenerative medicine

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Academic year 2022/2023

Course ID
BIO0216B Pds 306-TB
Teacher
Prof.ssa Benedetta Bussolati (Lecturer)
Modular course
Degree course
[0101M21] Molecular Biotechnology
Year
2nd year
Teaching period
To be defined
Type
Distinctive
Credits/Recognition
5
Course disciplinary sector (SSD)
MED/46 - medical and biotechnology laboratory techniques
Delivery
Formal authority
Language
English
Attendance
Obligatory
Type of examination
Oral
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Sommario del corso

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Course objectives

Knowledge of the molecular and cellular mechanisms involved in the pathogenesis of the main kidney diseases and of bio-technological techniques for their therapy.

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Results of learning outcomes

 

Knowledge of the molecular and cellular mechanisms involved in the pathogenesis of the main kidney diseases  and of bio-technological techniques for their therapy, with specific focus on regenerative medicine.

 

 

 

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Course delivery

On-line Moodle support for knowledge on renal pathology and transplant.

Frontal lessons and presentation/discussion of literature papers for the molecular and biotechnological approaches for kidney regeneration.

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Learning assessment methods

Oral examination and discussion of the literature data.

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Program

Pathogenetic mechanisms and development of molecular therapies:

Alterations of the immune system responsible for glomerular and tubulo-interstitial damage, autoimmunity, mechanism of the immune complex deposition. Strategies for the induction of tolerance. Mechanisms of glomerular permeability.

Allotransplant:

molecular and cellular mechanisms involved in the main clinical complications, theory and methodology for the development of techniques  aimed to induce a specific immuno-suppression, tolerance or to modify the organ immunogenicity.

 -Regenerative medicine:

Resident and bone-marrow derived stem cells in the regeneration of the glomerular and tubular damage; stem cells and gene therapy, bioreactors. 

Suggested readings and bibliography

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Didactic material (slides, text and articles) provided.



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Note

Le modalità di svolgimento dell'attività didattica potranno subire variazioni in base alle limitazioni imposte dalla crisi sanitaria in corso. In ogni caso è assicurata la modalità a distanza per tutto l'anno accademico

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Last update: 06/07/2022 12:02
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