- Oggetto:
- Oggetto:
The molecular basis of Nephrological therapies
- Oggetto:
The molecular bases of Nephrological therapies
- Oggetto:
Academic year 2021/2022
- Course ID
- BIO0169B Pds 306-TB
- Teacher
- Prof.ssa Benedetta Bussolati (Lecturer)
- Modular course
- THERAPEUTIC BIOTECHNOLOGY (BIO0169 Pds 306-TB)
- Degree course
- [0101M21] Molecular Biotechnology
- Year
- 2nd year
- Teaching period
- To be defined
- Type
- Distinctive
- Credits/Recognition
- 5
- Course disciplinary sector (SSD)
- MED/46 - scienze tecniche di medicina e di laboratorio
- Delivery
- Formal authority
- Language
- English
- Attendance
- Obligatory
- Type of examination
- Oral
- Oggetto:
Sommario del corso
- Oggetto:
Course objectives
Knowledge of the molecular and cellular mechanisms involved in the pathogenesis of the main kidney diseases and of bio-technological techniques for their therapy.
- Oggetto:
Results of learning outcomes
Knowledge of the molecular and cellular mechanisms involved in the pathogenesis of the main kidney diseases and of bio-technological techniques for their therapy, with specific focus on regenerative medicine.
- Oggetto:
Course delivery
On-line Moodle support for knowledge on renal pathology and transplant.
Frontal lessons and presentation/discussion of literature papers for the molecular and biotechnological approaches for kidney regeneration.
- Oggetto:
Learning assessment methods
Oral examination and discussion of the literature data.
- Oggetto:
Program
- Pathogenetic mechanisms and development of molecular therapies:
Alterations of the immune system responsible for glomerular and tubulo-interstitial damage, autoimmunity, mechanism of the immune complex deposition. Strategies for the induction of tolerance. Mechanisms of glomerular permeability.
- Allotransplant:
molecular and cellular mechanisms involved in the main clinical complications, theory and methodology for the development of techniques aimed to induce a specific immuno-suppression, tolerance or to modify the organ immunogenicity.
-Regenerative medicine:
Resident and bone-marrow derived stem cells in the regeneration of the glomerular and tubular damage; stem cells and gene therapy, bioreactors.
Suggested readings and bibliography
- Oggetto:
Didactic material (slides, text and articles) provided.
- Oggetto:
Note
Le modalità di svolgimento dell'attività didattica potranno subire variazioni in base alle limitazioni imposte dalla crisi sanitaria in corso. In ogni caso è assicurata la modalità a distanza per tutto l'anno accademico
- Oggetto:
