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Methods in Computational Biology I

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Methods in Computational Biology I

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Academic year 2023/2024

Course ID
BIO0221A Pds GEN
Teacher
Davide Marnetto
Degree course
[0101M22] Molecular Biotechnology
Year
2nd year
Teaching period
Second semester
Type
Elective
Credits/Recognition
2
Course disciplinary sector (SSD)
BIO/11 - molecular biology
Delivery
Formal authority
Language
English
Attendance
Obligatory
Type of examination
Written follewed by oral
Type of learning unit
modulo
Modular course
METHODS IN COMPUTATIONAL BIOLOGY (BIO0221 Pds GEN)
Prerequisites
Please refer to the integrated course.
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Sommario del corso

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Course objectives

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Results of learning outcomes

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Program

Methods to analyze genetic variation

  • Introduction to genetic variation: allele and genotype frequency, nucleotide diversity, heterozygosity, Hardy-Weinberg Equilibrium
  • Genetic Drift and its implications: the Wright-Fisher model
  • Population structure: isolation by distance, Fst and Wahlund effect 
  • Visualizing genetic diversity: Principal Component Analysis
  • Recombination, Linkage Disequilibrium and haplotypes
  • computational methods in the analysis of Archaic human genomes
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Course delivery

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Learning assessment methods

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Si prega di consultare il corso integrato.

Suggested readings and bibliography



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    Enrollment closing date
    31/12/2022 at 23:55
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