Vai al contenuto principale
Coronavirus: aggiornamenti per la comunità universitaria / Coronavirus: updates for UniTo Community
Oggetto:
Oggetto:

Molecular Therapy in Nephrology

Oggetto:

Terapie molecolari in Nefrologia

Oggetto:

Academic year 2019/2020

Course ID
BIO0144
Teacher
Prof.ssa Benedetta Bussolati
Degree course
[0101M21] Molecular Biotechnology
Year
2nd year
Type
Distinctive
Credits/Recognition
7
Course disciplinary sector (SSD)
MED/14 - nefrologia
Delivery
Formal authority
Language
Italian
Attendance
Obligatory
Type of examination
Oral
Type of learning unit
modulo
Modular course
THERAPEUTIC BIOTECHNOLOGY (BIO0169 Pds 306-TB)
Prerequisites
Basic knowledge on physiology, histology, cell and molecular biology and immunology.
Oggetto:

Sommario del corso

Oggetto:

Course objectives

Knowledge of the molecular and cellular mechanisms involved in the pathogenesis of the main kidney diseases  and of bio-technological techniques for their therapy.

Oggetto:

Results of learning outcomes

Knowledge of the molecular and cellular mechanisms involved in the pathogenesis of the main kidney diseases  and of bio-technological techniques for their therapy, with specific focus on regenerative medicine.

Oggetto:

Program

Pathogenetic mechanisms and development of molecular therapies:

Alterations of the immune system responsible for glomerular and tubulo-interstitial damage, autoimmunity, mechanism of the immune complex deposition. Strategies for the induction of tolerance. Mechanisms of glomerular permeability.

Allotransplant:

molecular and cellular mechanisms involved in the main clinical complications, theory and methodology for the development of techniques  aimed to induce a specific immuno-suppression, tolerance or to modify the organ immunogenicity.

- Xenotranplant:

antigens and molecular mechanisms involved in the rejection of a xenogenic transplant, theory and methodology for the development of techniques  aimed to improve the biocompatibility.

 -Regenerative medicine:

Resident and bone-marrow derived stem cells in the regeneration of the glomerular and tubular damage; stem cells and gene therapy, bioreactors. 

Oggetto:

Course delivery

Frontal lessons and presentation/discussion of literature papers.

Oggetto:

Learning assessment methods

Oral examination

Suggested readings and bibliography

Oggetto:

Didactic material (slides, text and articles) provided.  



Enroll
  • Open
    Enrollment opening date
    01/03/2020 at 00:00
    Enrollment closing date
    31/12/2022 at 23:55
    Oggetto:
    Last update: 27/12/2019 11:30
    Location: https://www.molecularbiotechnology.unito.it/robots.html
    Non cliccare qui!