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Oggetto:
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Molecular Dynamics of Cellular Processes

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Molecular Dynamics of Cellular Processes

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Academic year 2021/2022

Course ID
BIO0167A Pds 306-TB
Teachers
Prof.ssa Mara Brancaccio
Prof. Alessandro Bertero
Degree course
[0101M21] Molecular Biotechnology
Year
1st year
Teaching period
First semester
Type
Distinctive
Credits/Recognition
5
Course disciplinary sector (SSD)
BIO/13 - biologia applicata
Delivery
Formal authority
Language
English
Attendance
Optional
Type of examination
Oral
Type of learning unit
modulo
Modular course
FUNCTIONAL GENOMICS (BIO0167 Pds 306-TB)
Prerequisites
Good knowledge in molecular and cellular biology
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Sommario del corso

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Course objectives

The aim of the course is to deepen the knowledge on the molecular mechanisms relevant to post-transcriptional gene expression, which are of particular relevance and interest in the field of cellular biology. The aims are to provide new knowledge based on high impact research published in recent years in international journals. Teaching also aims to stimulate students' interest in recent and leading edge research in the field of cellular biology through critical reading and collective discussion of highly relevant scientific articles.

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Results of learning outcomes

At the end of the course the student:

- will know in detail and in depth the molecular mechanisms underlying the cellular processes studied

- will acquire the ability to read and criticize other relevant scientific articles where new discoveries are presented and discussed

- will have the ability to critically evaluate the scientific research presented during lessons

-can acquire the ability to read articles in English and structure scientific presentations by identifying key concepts and major issues

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Program

The program is based on the deepening of key scientific issues coming out in recent publications.

The topics covered will address the molecular mechanisms underlying post-transcriptional regulation at the RNA and protein level. The program will cover  alternative splicing and polyadenylation, mRNA modification and homeostasis, protein folding and degradation, and regulation of stress responses.

These aspects will be examined in different areas of biomedicine, including cancer, neural, cardiovascular, and immune biology.

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Course delivery

To achieve the learning objectives frontal lessons are used, with a high degree of interactivity to stimulate student involvement in discussing the topics presented.

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Learning assessment methods

Verification of learning involves a final oral exam that involves discussing the topics presented  in the lesson.

Suggested readings and bibliography

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Scientific publications selected and provided by the teacher.



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Notes

Le modalità di svolgimento dell'attività didattica potranno subire variazioni in base alle limitazioni imposte dalla crisi sanitaria in corso. In ogni caso è assicurata la modalità a distanza per tutto l'anno accademico.

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